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Published TCIMAIL newest issue No.197
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CAS RN: 74711-43-6 | Product Number: Z0021
Zaltoprofen
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-(10,11-Dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€56.00
|
1 | 9 |
|
| 5G |
€194.00
|
1 | 8 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | Z0021 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__4O__3S = 298.36 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 74711-43-6 |
| Reaxys Registry Number | 6770548 |
| PubChem Substance ID | 160871191 |
| Merck Index (14) | 10112 |
| MDL Number | MFCD00864323 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 135.0 to 139.0 °C |
Properties (reference)
| Melting Point | 137 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Methanol |
| Solubility (slightly sol. in) | Benzene, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 277-973-5 |
| RTECS# | HQ2526700 |
Transport Information:
| HS Number | 2934999090 |
Application
Studies on Nonsteroidal Anti-Inflammatory Drugs (NSAID)
References
Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells
Zaltoprofen inhibits bradykinin-induced responses by blocking the activation of second messenger signaling cascades in rat dorsal root ganglion cells
H. Tang, A. Inoue, K. Oshita, K. Hirate, Y. Nakata, Neuropharmacology 2005, 48, 1035.
Pharmacological investigations of the new antiinflammatory agent 2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid. 1st Communication: Inhibitory effects on rat paw edema
K. Tsurumi, K. Kyuki, M. Niwa, S. Kokuba, H. Fujimura, Arzneim.-Forsch. 1986, 36, 1796.
Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,f]thiepin-2-yl)propionic acid in rat and mouse
T. Kameyama, T. Nabeshima, S. Yamada, M. Sato, Arzneim.-Forsch. 1987, 37, 19.
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