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CAS RN: 168273-06-1 | Product Number: R0205
Rimonabant
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Purity: >98.0%(HPLC)
Synonyms:
- 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
- SR 141716
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€153.00
|
1 | 1 |
|
| 100MG |
€367.00
|
Contact Us | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | R0205 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__2__1Cl__3N__4O = 463.79 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 168273-06-1 |
| Reaxys Registry Number | 7231571 |
| PubChem Substance ID | 468592783 |
| MDL Number | MFCD04034714 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. H371 : May cause damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. |
Related Laws:
| RTECS# | UQ6279632 |
Transport Information:
| HS Number | 2933399990 |
Application
Rimonabant: A Selective Cannabinoid-1 Receptor (CB1) Antagonist.
Rimonabant (SR141716) is a selective cannabinoid-1 receptor (CB1) antagonist. CB1 is a G protein-coupled cannabinoid receptor that are found in the nervous system, and the body uses it to control food intake. It has been reported that rimonabant can help mammals to reduce food intake and to lose weight by blocking CB1 receptors. In clinical, rimonabant was withdrawn in 2008 due to serious psychiatric side effects. (The product is for research purpose only.)
References
- Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors
- Keynote review: Medicinal chemistry strategies to CB1 cannabinoid receptor antagonists
- The psychiatric side-effects of rimonabant
- Development and validation of a high-performance liquid chromatographic method for bioanalytical application with rimonabant
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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