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Published TCIMAIL newest issue No.197
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CAS RN: 83-79-4 | Product Number: R0090
Rotenone
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Purity: >95.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
137,00 €
|
8 | ≥100 |
|
| 25G |
438,00 €
|
3 | 2 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | R0090 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__2O__6 = 394.42 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 83-79-4 |
| Reaxys Registry Number | 99070 |
| PubChem Substance ID | 135727168 |
| Merck Index (14) | 8271 |
| MDL Number | MFCD09025614 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystaline |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation | -113 to -117 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 183 °C |
| Boiling Point | 220 °C/0.5 mmHg |
| Specific Rotation | -114° (C=1,CHCl3) |
| Solubility in water | Insoluble |
| Degree of solubility in water | 0.2 mg/l 20 °C |
| Solubility (soluble in) | Alcohol, Ether, Acetone, Chloroform |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H300 + H310 : Fatal if swallowed or in contact with skin. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H370 : Causes damage to organs. H372 : Causes damage to organs through prolonged or repeated exposure. H373 : May cause damage to organs through prolonged or repeated exposure. H335 : May cause respiratory irritation. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P273 : Avoid release to the environment. P260 : Do not breathe dust. P262 : Do not get in eyes, on skin, or on clothing. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P391 : Collect spillage. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor. |
Related Laws:
| EC Number | 201-501-9 |
| RTECS# | DJ2800000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | II |
| HS Number | 2932990090 |
Application
Mitophagy research
References
- PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
- Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
- Impaired mitochondrial biogenesis contributes to depletion of functional mitochondria in chronic MPP+ toxicity: dual roles for ERK1/2
- Spare Respiratory Capacity Rather Than Oxidative Stress Regulates Glutamate Excitotoxicity after Partial Respiratory Inhibition of Mitochondrial Complex I with Rotenone
Application
Reagent for Parkinson's disease model
References
- Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.
- Paraquat- and rotenone-induced models of Parkinson's disease.
PubMed Literature
Articles/Brochures
TCIMAIL
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