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CAS RN: 132-20-7 | Product Number: P2271
Pheniramine Maleate
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
69,00 €
|
4 | 35 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P2271 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__2__0N__2·C__4H__4O__4 = 356.42 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 132-20-7 |
| Related CAS RN | 86-21-5 |
| Reaxys Registry Number | 3813903 |
| PubChem Substance ID | 253660476 |
| Merck Index (14) | 7235 |
| MDL Number | MFCD00079250 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 %(total of Ion-Pair) |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 106.0 to 110.0 °C |
Properties (reference)
| Melting Point | 108 °C |
| Maximum Absorption Wavelength | 262 nm |
| Solubility (slightly sol. in) | Benzene, Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 205-051-4 |
| RTECS# | UT0175000 |
Transport Information:
| HS Number | 2933399990 |
Application
Pheniramine Maleate: A Histamine H1-Receptor Antagonist
Pheniramine maleate, a first generation antihistamine, is a histamine H1-receptor antagonist. It appears to compete with histamine for histamine H1-receptor sites on effector cells, and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. It also has anticholinergic and moderate sedative effects. On the other hand, pheniramine has been reported it as a corrosion inhibitor for mild steel in hydrochloric acid solution.
References
- Histamine antagonists. γ,γ-Disubstituted N,N-dialkyl-propylamines
- Inhibition of histamine-induced human conjunctival epithelial cell responses by ocular allergy drugs
- Simultaneous determination of pseudoephedrine, pheniramine, guaifenesin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography
- Spinal anesthesia with diphenhydramine and pheniramine in rats
- Inhibition of mild steel corrosion in acid solution by Pheniramine drug: Experimental and theoretical study
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