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CAS RN: 78712-43-3 | Product Number: O0419
Ozagrel Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (E)-3-[4-(Imidazol-1-ylmethyl)phenyl]propenoic Acid Hydrochloride
- trans-4-[(1-Imidazolyl)methyl]cinnamic Acid Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
92,00 €
|
2 | 29 |
|
| 5G |
299,00 €
|
2 | ≥40 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| Product Number | O0419 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__2N__2O__2·HCl = 264.71 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 78712-43-3 |
| Related CAS RN | 82571-53-7&189224-26-8 |
| Reaxys Registry Number | 5173590 |
| PubChem Substance ID | 253659529 |
| Merck Index (14) | 6980 |
| MDL Number | MFCD06795644 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | 5.0 to 8.0 % |
Properties (reference)
| Melting Point | 217 °C |
| Solubility in water | Soluble |
| Degree of solubility in water | 181 g/l 37 °C |
| Solubility (slightly sol. in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| RTECS# | UD3380000 |
Transport Information:
| HS Number | 2933299090 |
Application
強力かつ選択的なトロンボキサンA2合成酵素 (TXA2合成酵素) 阻害剤，オザグレル
Thromboxane A2 (TXA2) is an important metabolite of arachidonic acid cascade involved in a variety of cellular functions and diseases. TXA2 synthase activity is selectively inhibited by Ozagrel.
References
- Highly selective inhibitors of thromboxane synthetase. 1. Imidazole derivatives
- Effect of thromboxane A2 inhibitors on allergic pulmonary inflammation in mice
- Research and development of ozagrel, a highly selective inhibitor of TXA2 synthase
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