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Published TCIMAIL newest issue No.197
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CAS RN: 165450-17-9 | Product Number: N1112
Neotame
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N-[N-(3,3-Dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-Methyl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
16,00 €
|
1 | 33 |
|
| 5G |
38,00 €
|
1 | 28 |
|
| 25G |
125,00 €
|
1 | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N1112 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__0N__2O__5 = 378.47 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 165450-17-9 |
| Related CAS RN | 243116-62-3 |
| Reaxys Registry Number | 8352678 |
| PubChem Substance ID | 468592468 |
| Merck Index (14) | 6465 |
| MDL Number | MFCD09039056 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 84.0 to 88.0 °C |
Properties (reference)
| Melting Point | 86 °C |
| Specific Rotation | -57° (C=1,MeOH) |
| Solubility in water | Insoluble |
| Degree of solubility in water | 14.4 mg/l 25 °C |
| Solubility (soluble in) | Ethanol |
GHS
Related Laws:
| RTECS# | EK7796885 |
Transport Information:
| HS Number | 2924297099 |
Application
Neotame: An Artificial Nonnutritive Sweetener
Neotame is an artificial nonnutritive sweetener. It is between 6,000 and 10,000 times sweeter than sucrose [S0111] and 30-60 times sweeter than aspartame [A0997].1-3) It has been reported that the sweet taste receptor, a heterodimeric G protein coupled receptor (GPCR) protein, formed by the T1R2 and T1R3 subunits, recognizes several sweet compounds including neotame.4) (The product is for research purpose only.)
References
- 1) Neotame: discovery, properties, utility (a review)
- 2) Neotame (a review)
- 3) Artificial sweeteners - a review
- 4) From Small Sweeteners to Sweet Proteins: Anatomy of the Binding Sites of the Human T1R2_T1R3 Receptor
- 5) Simultaneous determination of nine intense sweeteners in foodstuffs by high performance liquid chromatography and evaporative light scattering detection-Development and single-laboratory validation
- 6) Simultaneous Determination of Nonnutritive Sweeteners in Foods by HPLC/ESI-MS
Product Documents (Note: Some products will not have analytical charts available.)
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