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CAS RN: 34562-97-5 | Product Number: N0998
Picamilon
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N-Nicotinoyl-GABA
- N-(3-Carboxypropyl)nicotinamide
- 4-(Nicotinamido)butyric Acid
- N-Nicotinoyl-γ-aminobutyric Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
80,00 €
|
1 | 21 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N0998 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__2N__2O__3 = 208.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 34562-97-5 |
| Reaxys Registry Number | 398732 |
| PubChem Substance ID | 253662452 |
| MDL Number | MFCD00186518 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 211.0 to 215.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 213 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2933399990 |
Application
GABAのプロドラッグ，ピカミロン
N-Nicotinoyl-γ-aminobutyric acid (picamilon), a prodrug of GABA [A0282], is able to cross the blood–brain barrier and then is hydrolyzed into GABA and nicotinic acid (niacin) [N0082].
References
- Evaluation of isonicotinoyl-γ-aminobutyric acid (GABA) and nicotinoyl-GABA as pro-drugs of GABA
- Research on the pharmacochemistry of some GABA and valproic acid derivatives
- Synthesis and evaluation of nicotinoylamino acid compounds as radiosensitizer
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