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CAS RN: 329003-65-8 | Product Number: M2289
Monosodium Risedronate Hemipentahydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Monosodium 1-Hydroxy-2-(3-pyridyl)ethylidene-1,1-diphosphonate Hemipentahydrate
- Risedronic Acid Monosodium Salt Hemipentahydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
€74.00
|
1 | 36 |
|
| 1G |
€486.00
|
1 | 33 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M2289 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__7H__1__0NNaO__7P__2·2^^1/__2H__2O = 350.13 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 329003-65-8 |
| Related CAS RN | 115436-72-1&105462-24-6 |
| Reaxys Registry Number | 6361090 |
| PubChem Substance ID | 135727372 |
| Merck Index (14) | 8232 |
| MDL Number | MFCD01706268 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Water | 11.9 to 13.9 % |
Properties (reference)
| Solubility in water | Soluble |
| Solubility (insoluble in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. H362 : May cause harm to breast-fed children. |
| Precautionary Statements | P263 : Avoid contact during pregnancy and while nursing. P260 : Do not breathe dust. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. |
Related Laws:
| RTECS# | SZ8567500 |
Transport Information:
| HS Number | 2933399990 |
Application
Pharmacology Studies
References
- Bisphosphonates Inhibit the Growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A Potential Route to Chemotherapy
- Effect of the bisphosphonate risedronate on bone metastases in a rat mammary adenocarcinoma model system
- Application of on-line Raman spectroscopy for characterizing relationships between drug hydration state and tablet physical stability
Application
Bone Resorption Inhibitors
Reference
- 1)Anti-bone resorption
- a)J. E. Dunford, K. Thompson, F. P. Coxon, S. P. Luckman, F. M. Hahn, C. D. Poulter, F. H. Ebetino, M. J. Rogers., J. Pharmacol. Exp. Ther. 2001, 296, 235.
- b)E. Hiroi-Furuya, T. Kameda, K. Hiura, H. Mano, K. Miyazawa, Y. Nakamaru, M. Watanabe-Mano, N. Okuda, J. Shimada, Y. Yamamoto, Y. Hakeda, M. Kumegawa, Calcif. Tissue Int. 1999, 64, 219.
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