Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 74103-07-4 | Product Number: K0053
Ketorolac Tromethamine
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- Ketorolac Tris Salt
- (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid Tris Salt
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€45.00
|
1 | 1 |
|
| 5G |
€175.00
|
3 | 13 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | K0053 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__3NO__3·C__4H__1__1NO__3 = 376.41 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 74103-07-4 |
| Related CAS RN | 74103-06-3 |
| Reaxys Registry Number | 6463165 |
| PubChem Substance ID | 253661330 |
| Merck Index (14) | 5306 |
| MDL Number | MFCD00887595 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 167 °C |
| Maximum Absorption Wavelength | 322(MeOH) nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| RTECS# | UY7759900 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933998090 |
Application
Ketorolac Tromethamine: A Non-Selective Cyclooxygenase (COX) Inhibitor with Strong Analgesic Activity
Ketorolac tromethamine is a non-steroidal anti-inflammatory drug (NSAID) with strong analgesic activity. Ketorolac is a non-selective cyclooxygenase (COX) inhibitor. Thus, it reduces prostaglandin synthesis. Ketorolac is the racemic mixture of (-)-S and (+)-R enantiomers. Most of its analgesic and COX inhibitory activity is retained in the S-isomer. Besides, some formulations for controlled release of ketorolac tromethamine have been reported. Ketorolac and its metabolites are excreted primarily by the kidneys. For your reference, [B4934] is used as a synthetic intermediate of ketorolac. (The product is for research purpose only.)
References
- The analgesic and anti-inflammatory profile of ketorolac and its tromethamine salt
- Ketorolac tromethamine absorption, distribution, metabolism, excretion, and pharmacokinetics in animals and humans
- Ketorolac. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential
- Semiinterpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine
- Ketorolac tromethamine formulations: an overview
- HPTLC determination of ketorolac tromethamine
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.