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Published TCIMAIL newest issue No.197
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CAS RN: 132-69-4 | Product Number: B3751
Benzydamine Hydrochloride
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Purity: >97.0%(T)(HPLC)
Synonyms:
- 1-Benzyl-3-[3-(dimethylamino)propoxy]-1H-indazole Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€37.00
|
1 | 14 |
|
| 25G |
€118.00
|
1 | 9 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B3751 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__3N__3O·HCl = 345.87 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 132-69-4 |
| Related CAS RN | 642-72-8 |
| Reaxys Registry Number | 4282836 |
| PubChem Substance ID | 160871060 |
| Merck Index (14) | 1122 |
| MDL Number | MFCD00078957 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Argentometric Titration) | min. 97.0 % |
| Melting point | 157.0 to 162.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 160 °C |
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 205-076-0 |
| RTECS# | NK7875000 |
Transport Information:
| HS Number | 2933998090 |
Application
Pharmacology Studies
References
- Synthesis and Biological Evaluation of Novel Pyrazoles and Indazoles as Activators of the Nitric Oxide Receptor, Soluble Guanylate Cyclase
- In vivo metabolism and antiinflammatory activity of benzydamine hydrochloride in rats treated with carrageenin
Application
Formulation Studies
References
- Development and in vitro/in vivo testing of mucoadhesive buccal patches releasing benzydamine and lidocaine
- Benzydamine hydrochloride buccal bioadhesive gels designed for oral ulcers: Preparation, rheological, textural,mucoadhesive and release properties
- S. Y. Karavana, P. Gueneri, G. Ertan, Pharm. Dev. Technol. 2009, 14, 623.
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