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CAS RN: 5451-09-2 | Product Number: A0325
5-Aminolevulinic Acid Hydrochloride
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Purity: >98.0%(T)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
€17.00
|
Contact Us | ≥40 |
|
| 1G |
€53.00
|
23 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A0325 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__5H__9NO__3·HCl = 167.59 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Hygroscopic |
| CAS RN | 5451-09-2 |
| Related CAS RN | 106-60-5 |
| Reaxys Registry Number | 3690651 |
| PubChem Substance ID | 87561977 |
| SDBS (AIST Spectral DB) | 4767 |
| Merck Index (14) | 446 |
| MDL Number | MFCD00012869 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(Argentometric Titration) | min. 98.0 % |
| Solubility in Water | almost transparency |
Properties (reference)
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 226-679-5 |
| RTECS# | OI1640000 |
Transport Information:
| HS Number | 2922500090 |
Application
5-Aminolevulinic acid (5-ALA): A Diagnostic Agent for Tumors Tissue
5-Aminolevulinic acid (5-ALA), a natural biochemical precursor of heme, is metabolized in a series of enzymatic reactions to fluorescent protoporphirin IX (PpIX) in the course of heme synthesis. 5-ALA is preferentially taken up by tumour tissue and intracellularly metabolised to PpIX which accumulates in tumor cells. Following excitation with blue light (λ=400 to 410 nm), the PpIX, which has accumulated selectively in the malignant tissue, emits a strong red PplX fluorescence (the peak is at 635 nm). Therefore, 5-ALA is often used to visualize tumorous tissue. (The product is for research purpose only.)
References
- Photosensitization of murine tumor, vasculature and skin by 5-aminolevulinic acid-induced porphyrin
- Prodrugs of 5-aminolevulinic acid for photodynamic therapy
- 5-aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells
- 5-Aminolevulinic acid-based photodynamic therapy: clinical research and future challenges (a review)
- The stability of 5-aminolevulinic acid in solution
- Liquid chromatography assay for 5-aminolevulinic acid: Application to in vitro assessment of skin penetration via Dermaportation
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