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CAS RN: 555-57-7 | Product Number: M2618
Pargyline
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Purity: >98.0%(GC)(T)
Synonyms:
- N-Methyl-N-(2-propyn-1-yl)benzylamine
- N-Methyl-N-propargylbenzylamine
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
A$245.00
|
3 | 6 |
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* ChemSupply Australia Pty Ltd (Phone: 08-8440-2000 / email: sales@chemsupply.com.au)
| Product Number | M2618 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__1H__1__3N = 159.23 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 555-57-7 |
| Reaxys Registry Number | 1938132 |
| PubChem Substance ID | 354333810 |
| Merck Index (14) | 7038 |
| MDL Number | MFCD00008576 |
Specifications
| Appearance | Colorless to Light yellow to Light orange clear liquid |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Boiling Point | 90 °C/4 mmHg |
| Flash point | 84 °C |
| Specific Gravity (20/20) | 0.95 |
| Refractive Index | 1.52 |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. H227 : Combustible liquid. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P403 + P235 : Store in a well-ventilated place. Keep cool. P405 : Store locked up. |
Related Laws:
| RTECS# | DP6475000 |
Transport Information:
| UN Number | UN2810 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2921.49-000 |
Application
Pargyline: An Irreversible Selective MAO-B Inhibitor.
Monoamine oxidase B (MAO-B) is a mitochondrial outer membrane flavoenzyme, which keeps the norepinephrine concentration in the axoplasm low. Therefore, MAO-B is a well-known target for antidepressant and neuroprotective agents. Pargyline is an irreversible selective MAO-B inhibitor. Pargyline is used to treat moderate to severe hypertension. Currently, pargyline is used as an antiparkinson agent. (The product is for research purpose only.)
References
- The acetylenic monoamine oxidase inhibitors clorgyline, deprenyl, pargyline, and J-508: their properties and applications (a review)
- Metabolism of monoamine oxidase inhibitors (a review)
- Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders
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