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CAS RN: 329196-48-7 | Product Number: A3537

SANT-2


Purity: >98.0%(T)(HPLC)
Synonyms:
  • N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide
  • N-[3-[1H-Benzo[d]imidazol-2-yl]-4-chlorophenyl]-3,4,5-triethoxybenzamide
Product Documents:
10MG
A$488.00
≥60  Contact Us
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Product Number A3537
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__6H__2__6ClN__3O__4 = 479.96 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Air Sensitive,Heat Sensitive
CAS RN 329196-48-7
Reaxys Registry Number 12773727
Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 215.0 to 219.0 °C
NMR confirm to structure
Properties (reference)
Melting Point 217 °C
GHS
Related Laws:
Transport Information:
H.S.code* 2933.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
SANT-2: A Smoothened (Smo) Receptor Antagonist

SANT-2 is a Smoothened (Smo) receptor antagonist. Smo, a Class Frizzled (Class F) G protein-coupled receptors, mediates Hedgehog (Hh) signaling that controls growth, cell fate decisions, and morphogenesis during development. There are reports that SANT-2 inhibits Smo activity and Hh signaling induced by an N-terminal fragment of sonic hedgehog (Shh). In addition, SANT-2 has been used in cancer research, as aberrant activation of the Hh signaling pathway has been implicated in a variety of cancers.

References


Product Documents (Note: Some products will not have analytical charts available.)
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