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CAS RN: 165800-06-6 | Product Number: Z0031
Zoledronic Acid Monohydrate
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic Acid Monohydrate
Product Documents:
Size | Unit Price | Belgium | Japan* | Quantity |
---|---|---|---|---|
1G |
€35.00
|
2 | 24 |
|
5G |
€117.00
|
1 | 15 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Product Number | Z0031 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__5H__1__0N__2O__7P__2·H__2O = 290.11 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 165800-06-6 |
Related CAS RN | 118072-93-8 |
Reaxys Registry Number | 9667036 |
PubChem Substance ID | 253662255 |
Merck Index (14) | 10187 |
MDL Number | MFCD00867791 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Water | 5.5 to 8.8 % |
NMR | confirm to structure |
Properties (reference)
Melting Point | 245 °C(dec.) |
Degree of solubility in water | 7 g/l 25 °C |
Solubility (insoluble in) | Methanol, Ethanol |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. |
Related Laws:
RTECS# | SZ8562450 |
Transport Information:
HS Number | 2933299090 |
Application
Bone Resorption Inhibitor
References
- 1)Bisphosphonates: From bench to bedside
- 2)Computational insights into binding of bisphosphates to farnesyl pyrophosphate synthase
- 3)Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite
- 4)Role of zoledronic acid in the prevention and treatment of osteoporosis
- 5)Emerging strategies and therapies for treatment of Paget’s disease of bone
- 6)The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy
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