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CAS RN: 2567792-04-3 | Product Number: U0150
(tert-Butoxyimino)-λ4-sulfanone
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Purity: >98.0%(GC)
Synonyms:
- N-Sulfinyl-tert-butoxyamine
- tBuONSO
- O-(tert-Butyl)-N-sulfinylhydroxylamine
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€95.00
|
13 | Contact Us |
|
| 10G |
€809.00
|
1 | 7 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | U0150 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__4H__9NO__2S = 135.18 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 2567792-04-3 |
| Reaxys Registry Number | 37039374 |
| PubChem Substance ID | 468593100 |
Specifications
| Appearance | Colorless to Light yellow clear liquid |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 75 °C/30 mmHg |
| Flash point | 27 °C |
| Specific Gravity (20/20) | 1.06 |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H226 : Flammable liquid and vapour. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P210 : Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 : Keep container tightly closed. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P403 + P235 : Store in a well-ventilated place. Keep cool. |
Related Laws:
Transport Information:
| UN Number | UN1993 |
| Class | 3 |
| Packing Group | III |
| HS Number | 2930909899 |
Application
Reagent for Primary Sulfonamide Synthesis
References
- Primary Sulfonamide Synthesis Using the Sulfinylamine Reagent N-Sulfinyl-O-(tert-butyl)hydroxylamine, t-BuONSO
- Direct one step dehydrogenative C-H sulfonimidation of unfunctionalized arenes: A conveneient protocol to emerging medicinal chemistry motifs without prefunctionalized arenes
Application
TCI Practical Example: Synthesis of primary sulfonamides using tBuONSO
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Used Chemicals
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Procedure
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To a solution of tBuONSO (400 mg, 2.96 mmol), in THF (anhydrous, 12 mL) was added p-tolylmagnesium bromide (19% in tetrahydrofuran, ca. 1mol/L, 4.4 mL, 4.4 mmol) at -78 °C and the mixture was stirred at -78 °C for 1 hour. The suspension was warmed at room temperature and stirred for overnight. After that, methanol (1 mL) was add to the reaction mixture and the solvent was removed under reduced pressure. The residue was purified by column chromatography (ethyl acetate:hexane = 0:1 - 1:4 on silica gel) to give 4-methylbenzenesulfonamide as a white solid (407 mg, 80%).
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Experimenter’s Comments
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The reaction mixture was monitored by UPLC.
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Analytical Data
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4-Methylbenzenesulfonamide
1H NMR (400 MHz, CDCl3); δ 7.70 (d, 2H, J = 8.4 Hz), 7.36 (d, 2H, J = 8.1 Hz), 7.27 (brs, 2H), 2.33 (s, 3H).
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Lead Reference
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- Primary Sulfonamide Synthesis Using the Sulfinylamine Reagent N‑Sulfinyl‑O‑(tert-butyl)hydroxylamine, t‑BuONSO
Articles/Brochures
TCIMAIL
[Product Highlights] Reagent for Primary Sulfonamide Synthesis[TCI Practical Example] Synthesis of Primary Sulfonamides Using tBuONSO
Product Documents (Note: Some products will not have analytical charts available.)
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