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CAS RN: 52-49-3 | Product Number: T3303
Trihexyphenidyl Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-Cyclohexyl-1-phenyl-3-(1-piperidyl)-1-propanol Hydrochloride
- α-Cyclohexyl-α-phenyl-1-piperidinepropanol Hydrochloride
- Benzhexol Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€91.00
|
1 | 22 |
|
| 25G |
€292.00
|
1 | 2 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3303 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__3__1NO·HCl = 337.93 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 52-49-3 |
| Related CAS RN | 144-11-6 |
| Reaxys Registry Number | 5667971 |
| PubChem Substance ID | 253661351 |
| Merck Index (14) | 9695 |
| MDL Number | MFCD00058212 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 247 °C(dec.) |
| Solubility in water | Slightly soluble |
| Degree of solubility in water | 10 g/l 25 °C |
| Solubility (soluble in) | Alcohol, Chloroform |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | TN2625000 |
Transport Information:
| HS Number | 2933399990 |
Application
Trihexyphenidyl Hydrochloride: A M1 Muscarinic Cholinergic Receptor Antagonist
Trihexyphenidyl hydrochloride is a M1 muscarinic cholinergic receptor antagonist, and is used for the treatment of parkinsonian syndrome. The exact mechanism of action in parkinsonian syndromes is not precisely understood, but it is known that trihexyphenidyl has a direct anti-spasmodic effect on smooth muscles and a control effect on extrapyramidal disorders which may be caused by certain drugs acting on the central nervous system. (The product is for research purpose only.)
References
- Parkinsonism. Clinical and neuropharmacologic aspects
- Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomine
- Comparative behavioral and neurochemical activities of cholinergic antagonists in rats
- Selective M1 muscarinic receptor antagonists disrupt memory consolidation of inhibitory avoidance in rats
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