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CAS RN: 2646-38-0 | Product Number: S0941
Sodium Chenodeoxycholate
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Purity: >97.0%(GC)
Synonyms:
- Chenodeoxycholic Acid Sodium Salt
- Sodium Chenodesoxycholate
- Chenodesoxycholic Acid Sodium Salt
- 3α,7α-Dihydroxy-5β-cholanic Acid Sodium Salt
- 3α,7α-Dihydroxy-5β-cholan-24-oic Acid Sodium Salt
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
23,00 €
|
2 | 9 |
|
| 1G |
76,00 €
|
2 | 7 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | S0941 |
| Purity / Analysis Method | >97.0%(GC) |
| Molecular Formula / Molecular Weight | C__2__4H__3__9NaO__4 = 414.56 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 2646-38-0 |
| Reaxys Registry Number | 4898788 |
| PubChem Substance ID | 354333736 |
| MDL Number | MFCD00065452 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 97.0 % |
| Purity(Nonaqueous Titration) | min. 96.0 % |
Properties (reference)
| Melting Point | 298 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | FZ2231000 |
Transport Information:
| HS Number | 2918199890 |
Application
Chenodeoxycholic Acid: A Naturally Occurring Bile Acid Having Suppressing Effects of Cholesterol and Cholic Acid Synthesis
Sodium chenodeoxycholate, a sodium salt of chenodeoxycholic acid, is a naturally occurring bile acid. Sodium chenodeoxycholate inhibits HMG-CoA-reductase and cholesterol-7α-hydroxylase, which are the rate-limiting step enzyme in cholesterol [C0318] and cholic acid [C0324] synthesis, respectively. Therefore, sodium chenodeoxycholate suppresses hepatic synthesis of both cholesterol and cholic acid, gradually replacing chenodeoxycholic acid in an expanded bile acid pool. In clinical use, these actions would contribute to gradual dissolution of cholesterol gallstones. (The product is for research purpose only.)
References
- Induced alterations in the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in the hamster.
- The effect of chenodeoxycholic acid (CDCA) on cholesterol absorption
- Chenodeoxycholic acid: a review of its pharmacological properties and therapeutic use
- Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity (a review)
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