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CAS RN: 108321-42-2 | Product Number: G0349
G418 Disulfate
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Purity: >90.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€80.00
|
1 | ≥60 |
|
| 5G |
€341.00
|
2 | 17 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | G0349 |
| Purity / Analysis Method | >90.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__0H__4__0N__4O__1__0·2H__2SO__4 = 692.70 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 108321-42-2 |
| Related CAS RN | 49863-47-0 |
| PubChem Substance ID | 125307225 |
| MDL Number | MFCD00058314 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 90.0 area% |
| Purity(with Total Nitrogen) | min. 90.0 % |
| Specific rotation [a]20/D | +110 to +120 deg(C=0.3, H2O, calcd.on anh.substance) |
Properties (reference)
| Specific Rotation | 111° (C=0.3,H2O) |
GHS
Related Laws:
Transport Information:
| HS Number | 2941900000 |
Application
G418: A Selective Agent for Genetically Engineered Eukaryotic Cells
G418 is an aminoglycoside antibiotic similar in structure to gentamicin [G0383] and is frequently used to selective agent for genetically engineered eukaryotic cells after transfection or transduction. It binds with the 70s and 80s ribosomes, and then it inhibits eukaryotic cell growth by inhibiting protein synthesis.
References
- A new dominant hybrid selective marker for higher eukaryotic cells
- Efficient selection for high-expression transfectants with a novel eukaryotic vector
- New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
- Rapid selection using G418 of high copy number transformants of Pichia pastoris for high-level foreign gene expression
- Expression of GFP using Pichia pastoris vectors with zeocin or G-418 sulphate as the primary selectable marker
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