Maintenance Notice (4:30 AM - 11:00 AM December 21, 2024): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 993-12-4 | Product Number: D2159
Dimethylthiophosphinoyl Chloride
×
![]()
×
Purity: >97.0%(GC)
Synonyms:
- Chlorodimethylphosphine Sulfide
- Dimethylphosphinothioyl Chloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€110.00
|
1 | 9 |
|
| 5G |
€416.00
|
Contact Us | 8 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D2159 |
| Purity / Analysis Method | >97.0%(GC) |
| Molecular Formula / Molecular Weight | C__2H__6ClPS = 128.55 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Moisture Sensitive,Heat Sensitive |
| CAS RN | 993-12-4 |
| Reaxys Registry Number | 906761 |
| PubChem Substance ID | 87568600 |
| MDL Number | MFCD00014454 |
Specifications
| Appearance | Colorless to Almost colorless clear liquid |
| Purity(GC) | min. 97.0 % |
Properties (reference)
| Boiling Point | 78 °C/15 mmHg |
| Specific Gravity (20/20) | 1.22 |
| Refractive Index | 1.54 |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H302 + H312 + H332 : Harmful if swallowed, in contact with skin or if inhaled. H314 : Causes severe skin burns and eye damage. H290 : May be corrosive to metals. |
| Precautionary Statements | P261 : Avoid breathing mist or vapours. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
Related Laws:
| EC Number | 213-606-7 |
Transport Information:
| UN Number | UN3265 |
| Class | 8 |
| Packing Group | II |
| HS Number | 2931599090 |
Application
A Condensing Reagent for the Peptide Synthesis in Alcohol Solvents
Experimental procedure1): A solution of Cbz-Asn-OH (79.8 mg, 0.3 mmol) and triethylamine (41.8 µL, 0.3 mmol) in methanol (2.6 mL) is cooled to -20 °C, and treated with a solution of Dimethylthiophosphinoyl Chloride (Mpt-Cl, 38 mg, 0.3 mmol) in methanol (0.9 mL), and the mixture stirred for 20 min. The solution is added to a solution of the tetrapeptide (1, 133.3 mg, 0.3 mmol) and triethylamine (41.8 µL, 0.3 mmol) in methanol (7.0 mL) and water (3.0 mL) at -20 °C. After the mixture has been stirred for 40 minutes the Cbz-Asn-OMpt solution and triethylamine (0.3 mmol each) are added and the stirring continued at -20 °C for 2 h and at 0 °C for 48 h. The precipitate is filtered and washed with chloroform, ethanol, water, and ether, and dried to give the pentapeptide (2, 173.7 mg, 84 %).
Peptide Synthesis, Glycosylation
References
- Peptide Synthesis
- Novel Glycosylation Reaction
- N-Acylation of Aminosugars
Application
Peptide Synthesis, Glycosylation
References
- Peptide Synthesis
- Novel Glycosylation Reaction
- N-Acylation of Aminosugars
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.