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CAS RN: 33818-15-4 | Product Number: C3445
Cytidine 5'-Diphosphocholine Sodium Salt
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Purity: >98.0%(HPLC)
Synonyms:
- Citicoline Sodium Salt
- CDP-choline Sodium Salt
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€48.00
|
1 | 1 |
|
| 5G |
€153.00
|
8 | 4 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3445 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__2__5N__4NaO__1__1P__2 = 510.31 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 33818-15-4 |
| Related CAS RN | 987-78-0 |
| Reaxys Registry Number | 4110040 |
| PubChem Substance ID | 468591112 |
| MDL Number | MFCD00037486 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 %(calcd.on anh.substance) |
| Water | max. 6.0 % |
Properties (reference)
| Melting Point | 250 °C(dec.) |
| Specific Rotation | 12.5° (C=1.0,H2O) |
| Maximum Absorption Wavelength | 280(HCl aq.) nm |
GHS
Related Laws:
| EC Number | 251-689-1 |
Transport Information:
| HS Number | 2934999090 |
Application
Citicoline: An Intermediate in the Biosynthesis of Cell Membrane Phospholipids Acting as a Neuroprotective Agent
Citicoline (cytidine 5'-diphosphocholine, CDP-choline) is an intermediate in the biosynthesis of cell membrane phospholipids. Therefore, citicoline can activate the biosynthesis of phospholipids in the neuronal membrane, increase cerebral metabolism and increase the level of various neurotransmitters, such as acetylcholine [A0084 (chloride)] and dopamine [A0305 (hydrochloride)]. Citicoline has shown beneficial effects in various central nervous system (CNS) injury models and neurodegenerative diseases, such as stroke, brain trauma, and Parkinson's disease. (The product is for research purpose only.)
References
- Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline (a review)
- Citicoline: neuroprotective mechanisms in cerebral ischemia
- Cytidine 5'-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
- Spectrophotometric determination of Citicoline sodium in pure form and pharmaceutical formulation
- Stability indicating LC method for the determination of citicoline sodium in injection formulation
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