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Published TCIMAIL newest issue No.197
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CAS RN: 18472-51-0 | Product Number: C3105
Chlorhexidine Digluconate (ca. 20% in Water)
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Purity:
Synonyms:
- 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] Digluconate (ca. 20% in Water)
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25ML |
€22.00
|
2 | ≥40 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3105 |
| Molecular Formula / Molecular Weight | C__2__2H__3__0Cl__2N__1__0·2C__6H__1__2O__7 = 897.76 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Light Sensitive,Heat Sensitive |
| CAS RN | 18472-51-0 |
| Related CAS RN | 55-56-1 |
| Reaxys Registry Number | 4348068 |
| PubChem Substance ID | 253660763 |
| Merck Index (14) | 2091 |
| MDL Number | MFCD00083599 |
Specifications
| Appearance | Colorless to Light yellow to Light orange clear liquid |
| Concentration(Nonaqueous Titration) | 18.0 to 21.0 w/w% |
Properties (reference)
| Specific Gravity (20/20) | 1.07 |
| Maximum Absorption Wavelength | 257(H2O) nm |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H410 : Very toxic to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P391 : Collect spillage. P337 + P313 : If eye irritation persists: Get medical advice/ attention. |
Related Laws:
| EC Number | 242-354-0 |
| RTECS# | DU1950000 |
Transport Information:
| UN Number | UN3082 |
| Class | 9 |
| Packing Group | III |
| HS Number | 2925290090 |
Application
Chlorhexidine Digluconate: A Skin Antiseptic and an Inhibitor of Matrix Metalloproteinase (MMP) Activity
Chlorhexidine digluconate, a biguanide, is a skin antiseptic in use in the health care setting with many potential applications for infection control. It is fungicidally active towards a wide range of Gram-positive and Gram-negative bacteria, including MRSA (methicillin-resistant Staphylococcus aureus). Within topical slow release vehicles, chlorhexidine digluconate is used for the treatment of periodontal disease. In addition, chlorhexidine digluconate is an efficient inhibitor of matrix metalloproteinase (MMP) activity. (The product is for research purpose only.)
References
- 1)Cationic antiseptics: diversity of action under a common epithet (a review)
- 2)Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic (a review)
- 3)Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery
- 4)Chlorhexidine stabilizes the adhesive interface: A 2-year in vitro study
- 5)Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine
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