Maintenance Notice (4:30 AM - 11:00 AM December 21, 2024): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 151060-21-8 | Product Number: B4354
Balofloxacin Dihydrate
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)-1-piperidyl]-4-oxoquinoline-3-carboxylic Acid Dihydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€55.00
|
1 | 1 |
|
| 5G |
€175.00
|
1 | 15 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | B4354 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__4FN__3O__4·2H__2O = 425.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 151060-21-8 |
| Related CAS RN | 127294-70-6 |
| Reaxys Registry Number | 8362117 |
| PubChem Substance ID | 253661053 |
| MDL Number | MFCD00864925 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 %(as Dihydrate) |
| Water | 6.5 to 10.5 % |
Properties (reference)
| Melting Point | 135 °C |
GHS
Related Laws:
| RTECS# | VB1993755 |
Transport Information:
| HS Number | 2933491090 |
Application
Balofloxacin: An 8-Methoxyfluoroquinolone Antibiotic
Balofloxacin (Q-35) is a fluoroquinolone antibiotic, in which a OMe group is substituted at the 8 position of the quinoline nucleus. In vitro, it has a broad spectrum of activity against Gram-positive bacteria (eg. Mycoplasma pneumoniae and Staphylococcus aureus including MRSA) which is almost equal to that of sparfloxacin [S0896] or tosufloxacin [T2506]. In contrast, its activity against Gram-negative bacteria is lower. In animal studies, balofloxacin do not exhibit any phototoxicity which is a toxicity of fluoroquinolone antibiotic, in general.
References
- In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumoniae
- Improved bactericidal activity of Q-35 against quinolone-resistant staphylococci
- Photostability and biological activity of fluoroquinolones substituted at the 8 position after UV irradiation
- Reduced phototoxicity of a fluoroquinolone antibacterial agent with a methoxy group at the 8 position in mice irradiated with long-wavelength UV light
- Laboratory and clinical study of balofloxacin (Q-35), a new fluoroquinolone, in urinary tract infection
- Development and validation of analytical method for estimation of Balofloxacin in bulk and pharmaceutical dosage form
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.